Search results for "functional divergence"

showing 7 items of 7 documents

The Role of Ancestral Duplicated Genes in Adaptation to Growth on Lactate, a Non-Fermentable Carbon Source for the Yeast Saccharomyces cerevisiae

2021

This article belongs to the Section Molecular Informatics.

GenomeInformationSystems_GENERALGene DuplicationGene Expression Regulation FungalGene duplicationComputingMilieux_COMPUTERSANDEDUCATIONPhenotypic responseRNA-SeqBiology (General)SpectroscopyGeneticsbiologyGene Expression Regulation DevelopmentalGeneral MedicineAdaptation PhysiologicalComputer Science ApplicationsChemistryMetabolic distanceWhole-genome duplicatesGenome FungalGlycolysisSmall-scale duplicatesSaccharomyces cerevisiae Proteinsphenotypic responseGeneralLiterature_INTRODUCTORYANDSURVEYQH301-705.5Saccharomyces cerevisiaesmall-scale duplicatesSaccharomyces cerevisiaeGeneralLiterature_MISCELLANEOUSArticleCatalysisEvolution MolecularInorganic ChemistryLactic AcidPhysical and Theoretical ChemistryQD1-999Molecular Biologymetabolic distanceAcidic stressacidic stressheat-shock proteinsGene Expression Profilingwhole-genome duplicatesOrganic ChemistryRobustness (evolution)biology.organism_classificationCarbonReactive oxygen responseYeastEvolvabilityGene OntologyHeat-shock proteinsAdaptationreactive oxygen responseFunctional divergenceInternational Journal of Molecular Sciences
researchProduct

Comparative Genomics Between Saccharomyces kudriavzevii and S. cerevisiae Applied to Identify Mechanisms Involved in Adaptation

2019

Yeasts belonging to the Saccharomyces genus play an important role in human-driven fermentations. The species S. cerevisiae has been widely studied because it is the dominant yeast in most fermentations and it has been widely used as a model eukaryotic organism. Recently, other species of the Saccharomyces genus are gaining interest to solve the new challenges that the fermentation industry are facing. One of these species is S. kudriavzevii, which exhibits interesting physiological properties compared to S. cerevisiae, such as a better adaptation to grow at low temperatures, a higher glycerol synthesis and lower ethanol production. The aim of this study is to understand the molecular basis…

0301 basic medicinelcsh:QH426-470Saccharomyces cerevisiaecomparative genomicsSaccharomyces cerevisiaeGenomeSaccharomyces03 medical and health sciences0302 clinical medicinepositive selectionfunctional divergenceGeneticsFunctional divergenceS. kudriavzeviiGeneGenetics (clinical)Comparative genomicsGeneticsbiologyComparative genomicsEvolutionary ratebiology.organism_classificationYeastPositive selectionlcsh:Genetics030104 developmental biology030220 oncology & carcinogenesisevolutionary rateMolecular MedicineSaccharomyces kudriavzeviiFunctional divergence
researchProduct

Conserved and newly acquired roles of PIF1 homologs in tomato (Solanum lycopersicum)

2021

ABSTRACTPHYTOCHROME INTERACTING FACTORS (PIFs) are transcription factors that interact with the photoreceptors phytochromes and integrate multiple signaling pathways related to light, temperature, defense and hormone responses. PIFs have been extensively studied inArabidopsis thaliana, but less is known about their roles in other species. Here, we investigate the role of the two homologs of PIF1 found in tomato (Solanum lycopersicum), namely PIF1a and PIF1b. Analysis of gene expression showed very different patterns, indicating a potential evolutionary divergence in their roles. At the protein level, light regulated the stability of PIF1a, but not PIF1b, further supporting a functional dive…

GeneticsPhytochromeArabidopsisMutantfood and beveragesArabidopsis thalianaNeofunctionalizationBiologySolanumRoot hair elongationbiology.organism_classificationFunctional divergence
researchProduct

Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

2010

International audience; BACKGROUND:The BCL-2 family of proteins includes pro- and antiapoptotic members acting by controlling the permeabilization of mitochondria. Although the association of these proteins with the outer mitochondrial membrane is crucial for their function, little is known about the characteristics of this interaction.METHODOLOGY/PRINCIPAL FINDINGS:Here, we followed a reductionist approach to clarify to what extent membrane-active regions of homologous BCL-2 family proteins contribute to their functional divergence. Using isolated mitochondria as well as model lipid Langmuir monolayers coupled with Brewster Angle Microscopy, we explored systematically and comparatively the…

Membrane lipidsLipid BilayersMolecular Sequence Databcl-X Proteinlcsh:MedicineApoptosisBiologyCell LineProtein–protein interactionMembrane LipidsMice03 medical and health sciences0302 clinical medicineProtein structureMembrane activityAnimalsHumansAmino Acid Sequence[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]lcsh:ScienceLipid bilayerInner mitochondrial membranebcl-2-Associated X Protein030304 developmental biologyMice KnockoutMicroscopy0303 health sciencesMultidisciplinarySequence Homology Amino Acidlcsh:RCytochromes cCell Biology/Cellular Death and Stress ResponsesFibroblastsPeptide FragmentsMitochondriaCell biologyBiochemistry/Molecular EvolutionMembrane proteinBiophysics/Membrane Proteins and Energy Transductionlcsh:QHydrophobic and Hydrophilic Interactions030217 neurology & neurosurgeryFunctional divergenceResearch ArticleBH3 Interacting Domain Death Agonist ProteinProtein BindingPLoS ONE
researchProduct

Varied response of underground and aboveground plant matter: functional diversity of three different vegetational types after translocation to reclai…

2019

The indicators of functional diversity are increasingly used to assess the conservation effectiveness of the most valuable habitats. However, little is known about the response of functional traits, their diversity, and divergence in plant communities after translocation. To assess how functional diversity changes on dry heath, meadow, and fen after translocation of entire turfs of vegetation from an airport area to the Botanical Garden in Radzionkow, we used leaf–height–seed (LHS) traits (specific leaf area, height, and seed mass) and vegetative traits (bud bank size, bud bank depth, and lateral spread). We also measured community weighted means and multifunctional diversity metrics (funct…

Specific leaf areaVegetative reproductionSoil Science010501 environmental sciencesDevelopmentBiology01 natural sciencesfunctional divergenceEnvironmental Chemistryvegetativetraits0105 earth and related environmental sciencesGeneral Environmental ScienceLHS traitsEcologyconservationfunctional richnessPlant community04 agricultural and veterinary sciencesVegetationvegetative traitsHabitat040103 agronomy & agriculture0401 agriculture forestry and fisheriesSpecies evennessSpecies richnesspostindustrial landhuman activitiesFunctional divergenceLand Degradation & Development
researchProduct

Comparative Genomics Between

2018

Yeasts belonging to the Saccharomyces genus play an important role in human-driven fermentations. The species S. cerevisiae has been widely studied because it is the dominant yeast in most fermentations and it has been widely used as a model eukaryotic organism. Recently, other species of the Saccharomyces genus are gaining interest to solve the new challenges that the fermentation industry are facing. One of these species is S. kudriavzevii, which exhibits interesting physiological properties compared to S. cerevisiae, such as a better adaptation to grow at low temperatures, a higher glycerol synthesis and lower ethanol production. The aim of this study is to understand the molecular basis…

positive selectionfunctional divergenceGeneticsevolutionary rateS. kudriavzeviiSaccharomyces cerevisiaecomparative genomicsOriginal ResearchFrontiers in genetics
researchProduct

Selection on Coding Regions Determined Hox7 Genes Evolution

2003

The important role of Hox genes in determining the regionalization of the body plan of the vertebrates makes them invaluable candidates for evolutionary analyses regarding functional and morphological innovation. Gene duplication and gene loss led to a variable number of Hox genes in different vertebrate lineages. The evolutionary forces determining the conservation or loss of Hox genes are poorly understood. In this study, we show that variable selective pressures acted on Hox7 genes in different evolutionary lineages, with episodes of positive selection occurring after gene duplications. Tests for functional divergence in paralogs detected significant differentiation in a region known to …

Molecular Sequence DataBiologyEvolution MolecularOpen Reading FramesNegative selectionGene DuplicationGene duplicationGene clusterGeneticsAnimalsHumansCoding regionAmino Acid SequenceHox geneMolecular BiologyGenePhylogenyEcology Evolution Behavior and SystematicsGeneticsLikelihood FunctionsGenes HomeoboxGenetic VariationSequence Analysis DNABody planEvolutionary biologyMultigene FamilyVertebratesFunctional divergenceMolecular Biology and Evolution
researchProduct